Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment-Reference-Cited by-同舟云学术

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Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment

Published:2017-12 Issue:6 Volume:32 Page:777-791.e6
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Turaj Anna H.,Hussain Khiyam,Cox Kerry L.,Rose-Zerilli Matthew J.J.,Testa James,Dahal Lekh N.,Chan H.T. Claude,James Sonya,Field Vikki L.,Carter Matthew J.,Kim Hyung J.,West Jonathan J.,Thomas Lawrence J.,He Li-Zhen,Keler Tibor,Johnson Peter W.M.,Al-Shamkhani Aymen,Thirdborough Stephen M.,Beers Stephen A.,Cragg Mark S.,Glennie Martin J.,Lim Sean H.

Funder

Cancer Research UK

Kay Kendall Leukaemia

Wessex Medical Research Innovation

Leuka Charity

John Goldman Fellowship

Southampton CRUK Centre Development

Celldex Therapeutics

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference59 articles.

1. CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase;Akiba;J. Biol. Chem.,1998

2. OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand;al-Shamkhani;Eur. J. Immunol.,1996

3. Constitutive CD27/CD70 interaction induces expansion of effector-type T cells and results in IFNgamma-mediated B cell depletion;Arens;Immunity,2001

4. Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation;Beers;Blood,2008

5. Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection;Beers;Blood,2010

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