Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation
Author:
Affiliation:
1. Tenovus Laboratory, Cancer Sciences Division, Southampton University School of Medicine, General Hospital, Southampton, United Kingdom; and
2. Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/112/10/4170/1481338/zh802208004170.pdf
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4. Mechanisms of killing by anti-CD20 monoclonal antibodies.;Glennie;Mol Immunol,2007
5. Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene.;Cartron;Blood,2002
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