Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1–mediated metabolism to the product 4′ hydroxy tangeretin-Reference-Cited by-同舟云学术

Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1–mediated metabolism to the product 4′ hydroxy tangeretin

Published:2018-08 Issue: Volume:50 Page:274-284
ISSN:0887-2333
Container-title:Toxicology in Vitro
language:en
Short-container-title:Toxicology in Vitro

Author:

Surichan Somchaiya,Arroo Randolph R.,Tsatsakis Aristidis M.,Androutsopoulos Vasilis P.

Funder

University of Crete

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference44 articles.

1. The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and p53/p21 upregulation;Androutsopoulos;J. Nutr. Biochem.,2013

2. Benzo[a]pyrene sensitizes MCF7 breast cancer cells to induction of G1 arrest by the natural flavonoid eupatorin–5–methyl ether via activation of cell signaling proteins and CYP1–mediated metabolism;Androutsopoulos;Toxicol. Lett.,2014

3. Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism;Androutsopoulos;Breast Cancer Res.,2008

4. Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450;Androutsopoulos;Cancer Lett.,2009

5. Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA–MB–468 breast cancer cells due to CYP1 activation;Androutsopoulos;Oncol. Rep.,2009

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