Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models

Author:

Jäckh Christine,Blatz Veronika,Fabian Eric,Guth Katharina,van Ravenzwaay Ben,Reisinger Kerstin,Landsiedel Robert

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference34 articles.

1. The Phenion (R) Full-Thickness Skin Model for percutaneous absorption testing;Ackermann;Skin Pharmacology and Physiology,2010

2. Xenobiotic metabolizing capabilities of the EpiDerm in vitro human skin equivalent: utility for assessing dermal biotransformation of pharmaceuticals and environmental chemicals;Bolmarcich;Journal of Investigative Dermatology,2006

3. N-Acetyltransferase 1 enzyme activities in subtypes of HaCaT cells compared to primary keratinocytes;Bonifas;Naunyn-Schmiedebergs Archives of Pharmacology,2009

4. Evaluation of Cytochrome P450 1 (CYP1) and N-Acetyltransferase 1 (NAT1) activities in HaCaT cells: Implications for the development of in vitro techniques for predictive testing of contact sensitizers;Bonifas;Toxicology in Vitro,2010

5. Bornstein, BF. (2000). Activities of N-Acetyltransferases NAT1 and NAT2 in human tissues. Thesis/Dissertation. Technical University of Munich, Germany.

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