A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom–Up and Top–Down approaches

Author:

Scott Laurie,Eskes Chantra,Hoffmann Sebastian,Adriaens Els,Alepée Nathalie,Bufo Monica,Clothier Richard,Facchini Davide,Faller Claudine,Guest Robert,Harbell John,Hartung Thomas,Kamp Hennicke,Varlet Béatrice Le,Meloni Marisa,McNamee Pauline,Osborne Rosemarie,Pape Wolfgang,Pfannenbecker Uwe,Prinsen Menk,Seaman Christopher,Spielmann Horst,Stokes William,Trouba Kevin,Berghe Christine Van den,Goethem Freddy Van,Vassallo Marco,Vinardell Pilar,Zuang Valérie

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Reference46 articles.

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3. Eye irritation testing: the way forward. The report and recommendations of ECVAM workshop 34;Balls;Alternatives to Laboratory Animals,1999

4. Practical application of non-whole animal alternatives: summary of IRAG workshop on eye irritation testing. Interagency Regulatory Alternatives Group;Bradlaw;Food and Chemical Toxicology,1997

5. A summary report of the COLIPA international validation study on alternatives to the Draize rabbit eye irritation test;Brantom;Toxicology in Vitro,1997

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