An in vitro tool to assess cytochrome P450 drug biotransformation-dependent cytotoxicity in engineered HepG2 cells generated by using adenoviral vectors
Author:
Funder
European Commission
ALIVE Foundation
Publisher
Elsevier BV
Subject
Toxicology,General Medicine
Reference32 articles.
1. Simultaneous expression of plural forms of human cytochrome P450 at desired ratios in HepG2 cells: adenovirus-mediated tool for cytochrome P450 reconstitution;Aoyama;Drug Metab. Pharmacokinet.,2009
2. Use of recombinant adenovirus for metabolic engineering of mammalian cells;Becker;Methods Cell Biol.,1994
3. Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity;Bai;Mol. Cell. Biochem.,2004
4. Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathway;Bort;Biochem. Pharmacol.,1999
5. Human cytochrome P450 2E1 (CYP2E1): from genotype to phenotype;Carrière;Pharmacogenetics,1996
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