ATP-based cell viability assay is superior to trypan blue exclusion and XTT assay in measuring cytotoxicity of anticancer drugs Taxol and Imatinib, and proteasome inhibitor MG-132 on human hepatoma cell line HepG2

Author:

Nowak Elisabeth1,Kammerer Sarah1,Küpper Jan-Heiner1

Affiliation:

1. Institute of Biotechnology, Brandenburg University of Technology Cottbus-Senftenberg, Germany

Publisher

IOS Press

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine,Hematology,Physiology

Reference55 articles.

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2. Evaluation of the cytotoxicity of 10 chemicals in human and rat hepatocytes and in cell lines: Correlation between in vitro data and human lethal concentration;Ponsoda;Toxicology in Vitro,1995

3. Genetic and molecular factors in drug-induced liver injury: A review;Pachkoria;Current Drug Safety,2007

4. Taxol: A history of pharmaceutical development and current pharmaceutical concerns;Adams;Journal of the National Cancer Institute Monographs,1993

5. Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation;Cervello;International Journal of Molecular Medicine,2004

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