Bone-specific delivery and sustained release of diclofenac, a non-steroidal anti-inflammatory drug, via bisphosphonic prodrug based on the Osteotropic Drug Delivery System (ODDS)

Author:

Hirabayashi Hideki,Takahashi Toshiya,Fujisaki Jiro,Masunaga Taro,Sato Sachio,Hiroi Jun,Tokunaga Yuji,Kimura Sumihisa,Hata Takehisa

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference22 articles.

1. Theory and practice of site-specific drug delivery;Tomlinson;Adv. Drug Deliv. Rev.,1987

2. Chemical delivery systems;Border,1991

3. Bone blood flow: regional variation with skeletal maturation;Light,1984

4. Osteotropic Drug Delivery System (ODDS) based on bisphosphonic prodrug. I: Synthesis and in vivo characterization of osteotropic carboxyfluorescein;Fujisaki;J. Drug Target.,1995

5. Physicochemical characteristics of bisphosphonic carboxyfluorescein for osteotropic drug delivery;Fujisaki;J. Pharm. Pharmacol.,1996

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