Physicochemical Characterization of Bisphosphonic Carboxyfluorescein for Osteotropic Drug Delivery
Author:
Affiliation:
1. Pharmaceutical and Pharmacokinetic Research Laboratories, Fujisawa Pharmaceutical Company Ltd, 1−6, 2−chome, Kashima, Yodogawa-ku, Osaka 532, Japan
Abstract
Publisher
Oxford University Press (OUP)
Subject
Pharmaceutical Science,Pharmacology
Link
http://academic.oup.com/jpp/article-pdf/48/8/798/37017336/j.2042-7158.1996.tb03976.x.pdf
Reference6 articles.
1. Bisphosphonates: a new class of drugs in diseases of bone and calcium metabolism;Fleisch,1988
2. Osteotropic drug delivery system (ODDS) based on bisphosphonic prodrug. I: Synthesis and in vivo characterization of osteotropic carboxyfluorescein;Fujisaki;J. Drug Targeting,1995
3. The binding of pyrophosphonate and two diphosphonates by hydroxyapatite crystals;Jung;Calcif. Tissue Res.,1973
4. A Novel skeletal drug delivery system using self-setting calcium phosphate cement. 2. Physicochemical properties and drug release rate of the cement-containing indomethacin;Otsuka;J. Pharm. Sci.,1994
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