Polymer-bound camptothecin: initial biodistribution and antitumour activity studies

Author:

Caiolfa V.R,Zamai M,Fiorino A,Frigerio E,Pellizzoni C,d’Argy R,Ghiglieri A,Castelli M.G,Farao M,Pesenti E,Gigli M,Angelucci F,Suarato A

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference26 articles.

1. DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin;Hsiang;Cancer Res.,1989

2. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme–DNA complex;Hertzberg;Biochemistry,1989

3. Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumour activity;Kingsbury;J. Med. Chem.,1990

4. DNA topoisomerase I-targeted chemotherapy of human colon cancer in xenografts;Giovanella;Science,1989

5. Complete growth inhibition of human cancer xenografts in nude mice by treatment with 20-(S)-camptothecin;Giovanella;Cancer Res.,1991

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