Valproic Acid Thermally Destabilizes and Inhibits SpyCas9 Activity
Author:
Funder
Hessisches Ministerium für Wissenschaft und Kunst
Deutsche Forschungsgemeinschaft
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine
Reference41 articles.
1. CRISPR provides acquired resistance against viruses in prokaryotes;Barrangou;Science,2007
2. The next generation of CRISPR-Cas technologies and applications;Pickar-Oliver;Nat. Rev. Mol. Cell Biol.,2019
3. High-throughput functional genomics using CRISPR-Cas9;Shalem;Nat. Rev. Genet.,2015
4. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells;Fu;Nat. Biotechnol.,2013
5. Engineered CRISPR-Cas9 nucleases with altered PAM specificities;Kleinstiver;Nature,2015
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Molecular Marvels: Small Molecules Paving the Way for Enhanced Gene Therapy;Pharmaceuticals;2023-12-27
2. Development of a next-generation endogenous OCT4 inducer and its anti-aging effect in vivo;European Journal of Medicinal Chemistry;2023-09
3. Small Molecules for Enhancing the Precision and Safety of Genome Editing;Molecules;2022-09-23
4. Modulating CRISPR/Cas9 genome-editing activity by small molecules;DRUG DISCOV TODAY;2022
5. A PROTAC targets splicing factor 3B1;Cell Chemical Biology;2021-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3