Hitchhiking of Cas9 with nucleus-localized proteins impairs its controllability and leads to efficient genome editing of NLS-free Cas9-Reference-Cited by-同舟云学术

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Hitchhiking of Cas9 with nucleus-localized proteins impairs its controllability and leads to efficient genome editing of NLS-free Cas9

Published:2024-04 Issue:4 Volume:32 Page:920-934
ISSN:1525-0016
Container-title:Molecular Therapy
language:en
Short-container-title:Molecular Therapy

Author:

Zhang Wenfeng,Wang Haozheng,Luo Zhongtao,Jian Yingzhen,Gong Chenyu,Wang Hui,Lin Xinjian,Liu Meilin,Wang Yangmin,Shao Hongwei

Funder

National Natural Science Foundation of China

Science and Technology Planning Project of Guangdong Province

National Natural Science Foundation of China-Guangdong Joint Fund

Publisher

Elsevier BV

Reference28 articles.

1. Multiplex Genome Engineering Using CRISPR/Cas Systems;Cong;Science,2013

2. RNA-guided human genome engineering via Cas9;Mali;Science,2013

3. Influence of cargo size on Ran and energy requirements for nuclear protein import;Lyman;J. Cell Biol.,2002

4. Strategies for Optimization of the Clustered Regularly Interspaced Short Palindromic Repeat-Based Genome Editing System for Enhanced Editing Specificity;Wang;Hum. Gene Ther.,2022

5. Development of a Self-Restricting CRISPR-Cas9 System to Reduce Off-Target Effects;Wang;Mol. Ther. Methods Clin. Dev.,2020

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