Transient expression of factor VIII and a chronic high-fat diet induces ER stress and late hepatocyte oncogenesis
Author:
Publisher
Elsevier BV
Subject
Drug Discovery,Pharmacology,Genetics,Molecular Biology,Molecular Medicine
Reference15 articles.
1. Antioxidants reduce endoplasmic reticulum stress and improve protein secretion;Malhotra;Proc. Natl. Acad. Sci. USA.,2008
2. Ectopic FVIII expression and misfolding in hepatocytes as a cause for hepatocellular carcinoma;Kapelanski-Lamoureux;Mol. Ther.,2022
3. Eliminating Panglossian thinking in development of AAV therapeutics;Kaczmarek;Mol. Ther.,2021
4. Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response;Manno;Nat. Med.,2006
5. Induction of ER stress by an AAV5 BDD FVIII construct Is dependent on the strength of the hepatic-specific promoter;Fong;Mol. Ther. Methods Clin. Dev.,2020
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