RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency-Reference-Cited by-同舟云学术

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RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency

Published:2001-03 Issue:5 Volume:11 Page:693-696
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Collis Alan J,Foster Martyn L,Halley Frank,Maslen Christopher,McLay Iain M,Page Kenneth M,Redford E.Jane,Souness John E,Wilsher Nicola E

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference9 articles.

1. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

2. Molecular and cellular interactions in rheumatoid synovium

3. Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis

4. McLay, I. M.; Halley, F.; McKenna, J.; Souness, J. E.; Benning, V.; Birrell, M.; Burton, B.; Belvisi, M.; Collis, A.; Constan, A.; Foster, M. L.; Hele, D.; Jayyosi, Z.; Kelley, M.; Maslen, C.; Miller, G.; Ouldelhkim, M. C.; Page, K.; Phipps, S.; Pollock, K.; Porter, B.; Ratcliffe, A. J.; Redford, E. J.; Webber, S.; Slater, B.; Thybaud, V.; Wilsher, N. Bioorg. Med. Chem. 2001, 9, 537.

5. Pyrimidinylimidazole inhibitors of CSBP/P38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes

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