The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy-Reference-Cited by-同舟云学术

The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy

Published:2001-02 Issue:2 Volume:9 Page:537-554
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

McLay Iain M.,Halley Frank,Souness John E.,McKenna Jeffrey,Benning Veronique,Birrell Mark,Burton Brenda,Belvisi Maria,Collis Alan,Constan Alex,Foster Martyn,Hele David,Jayyosi Zaid,Kelley Mike,Maslen Chris,Miller Glen,Ouldelhkim Marie-Claude,Page Kenneth,Phipps Simon,Pollock Kenneth,Porter Barry,Ratcliffe Andrew J.,Redford Elisabeth J.,Webber Stephen,Slater Bryan,Thybaud Veronique,Wilsher Nicola

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference32 articles.

1. Bicyclic imidazoles as a novel class of cytokine biosynthesis inhibitors;Lee;Ann. N.Y. Acad. Sci.,1993

2. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis;Lee;Nature (London),1994

3. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells;Han;Science,1994

4. Review, pulmonary-allergy, dermatological, gastrointestinal and arthritis;Hanson;Expert Opin. Ther. Pat.,1997

5. Acyl-CoA:cholesterol O-acyltransferase (ACAT) inhibitors. 2.2-(1,3-Dioxan-2-yl)-4,5-diphenyl-1H-imidazoles as potent inhibitors of ACAT;Astles;J. Med. Chem.,1996

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