1. Bolton, D.; Forbes, I.T.; Hayward, C.J.; Piper, D.C.; Thomas, D.R.; Thompson, M.; Upton, N. Biomed. Chem. Lett., paper in press.
2. The effects of meprobamate, barbiturates, d-amphetamine and promazine on experimentally induced conflict in the rat
3. Unpublished results from Drug Metabolism and Pharmacokinetics Unit, SB.
4. In the quinindoline series, spectroscopic measurements confirm that there is a greater degree of intramolecular hydrogen bonding between the amino and carbonyl groups. For 1 the 1H NMR (270MHz, CDCl3) shows a broad 2H, s at 6.7-6.8 for the 4-NH2 group whereas the corresponding signal for 5 is too broad to be observed. Also supported by IR (KBr disc) data for 1 1680, 3390, 3500 and for 5 1640, 3330, 3440cm−1.
5. Syntheses of functionalised pyrido[2,3-b]indoles