Initial structure–activity relationship of a novel class of nonpeptidyl GnRH receptor antagonists: 2-arylindoles

Author:

Chu Lin,Hutchins Jennifer E.,Weber Ann E.,Lo Jane-Ling,Yang Yi-Tien,Cheng Kang,Smith Roy G.,Fisher Michael H.,Wyvratt Matthew J.,Goulet Mark T.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference11 articles.

1. Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence

2. Kardamakis, E.; Tzingounis, V. In Biomed. Health Res.; IOS Press, Vol. 22 (Bioactive Peptides in Drug Discovery and Design: Medical Aspects), 1999; pp 275–285, and references cited therein.

3. Chemistry and Molecular Biology in the Search for New LHRH Antagonists

4. Behre, H. M.; Nordhoff, V.; Nieschlag, E. Ovul. Induct. Update ‘98, Proc. World Conf., 2nd, 1997. Filicori, M., Flamigni, C., Eds.; Parthenon Publishing: Carnforth, UK (English) 1998; pp 107–113.

5. Discovery of a Novel, Potent, and Orally Active Nonpeptide Antagonist of the Human Luteinizing Hormone-Releasing Hormone (LHRH) Receptor

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