ΔF659 and F659S substitutions at the HS1 of FKS2 gene, along with E655A and W715L upstream and downstream substitutions, correlate with high ibrexafungerp MICs against Candida glabrata-Reference-Cited by-同舟云学术

ΔF659 and F659S substitutions at the HS1 of FKS2 gene, along with E655A and W715L upstream and downstream substitutions, correlate with high ibrexafungerp MICs against Candida glabrata

Published:2022-08 Issue:8 Volume:28 Page:1154.e5-1154.e8
ISSN:1198-743X
Container-title:Clinical Microbiology and Infection
language:en
Short-container-title:Clinical Microbiology and Infection

Author:

Mesquida Aina,Díaz-García Judith,Sánchez-Carrillo Carlos,Martín-Rabadán Pablo,Alcalá Luis,Muñoz Patricia,Escribano Pilar,Guinea Jesús

Publisher

Elsevier BV

Subject

Infectious Diseases,Microbiology (medical),General Medicine

Reference13 articles.

1. Fungal resistance to echinocandins and the MDR phenomenon in Candida glabrata;Healey;J Fungi (Basel),2018

2. De novo acquisition of resistance to SCY-078 in Candida glabrata involves FKS mutations that both overlap and are distinct from those conferring echinocandin resistance;Jimenez-Ortigosa;Antimicrob Agents Chemother,2017

3. Differential activity of the oral glucan synthase inhibitor SCY-078 against wild-type and echinocandin-resistant strains of Candida species;Pfaller;Antimicrob Agents Chemother,2017

4. Antifungal activity of SCY-078 and standard antifungal agents against 178 clinical isolates of resistant and susceptible Candida species;Schell;Antimicrob Agents Chemother,2017

5. In Vitro activity of Ibrexafungerp, a novel glucan synthase inhibitor against Candida glabrata isolates with FKS mutations;Nunnally;Antimicrob Agents Chemother,2019

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1. A Mini-Review of In Vitro Data for Candida Species, Including C. auris, Isolated during Clinical Trials of Three New Antifungals: Fosmanogepix, Ibrexafungerp, and Rezafungin;Journal of Fungi;2024-05-20

2. Ibrexafungerp: A narrative overview;Current Research in Microbial Sciences;2024

3. Trends in antifungal resistance in Candida from a multicenter study conducted in Madrid (CANDIMAD study): fluconazole-resistant C. parapsilosis spreading has gained traction in 2022;Antimicrobial Agents and Chemotherapy;2023-11-15

4. Novel Non-Hot Spot Modification in Fks1 of Candida auris Confers Echinocandin Resistance;Antimicrobial Agents and Chemotherapy;2023-06-15

5. The antifungal pipeline for invasive fungal diseases: what does the future hold?;Expert Review of Anti-infective Therapy;2023-04-20