Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms

Author:

Tsai Harrison K.ORCID,Brackett Diane G.ORCID,Szeto David,Frazier RyanORCID,MacLeay AllisonORCID,Davineni Phani,Manning Danielle K.,Garcia Elizabeth,Lindeman Neal I.,Le Long P.,Lennerz Jochen K.,Gibson Christopher J.,Lindsley R. Coleman,Kim Annette S.,Nardi Valentina

Funder

NIH

Publisher

Elsevier BV

Subject

Molecular Medicine,Pathology and Forensic Medicine

Reference38 articles.

1. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia;Nakao;Leukemia,1996

2. Targeting FLT3 mutations in AML: review of current knowledge and evidence;Daver;Leukemia,2019

3. Midostaurin plus chemotherapy for acute myeloid leukemia with a FLT3 mutation;Stone;N Engl J Med,2017

4. Selective inhibition of FLT3 by gilteritinib in relapsed or refractory acute myeloid leukaemia: a multicentre, first-in-human, open-label, phase 1-2 study;Perl;Lancet Oncol,2017

5. Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study;Whitman;Cancer Res,2001

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