Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca 2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay-Reference-Cited by-同舟云学术

Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca 2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay

Published:2017-01 Issue:1 Volume:25 Page:440-449
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Azimi Iman,Flanagan Jack U.,Stevenson Ralph J.,Inserra Marco,Vetter Irina,Monteith Gregory R.,Denny William A.

Funder

QUE Oncology Inc

University of Auckland Biopharma Initiative

Australian Research Council Future Fellowship

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference56 articles.

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2. Hypotensive Action and Increased Plasma Renin Activity by Ca²⁺ Antagonist (Nifedipine) in Hypertensive Patients

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4. Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1

5. A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

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