Investigation of human flap structure-specific endonuclease 1 (FEN1) activity on primer-template models and exploration of a substrate-based FEN1 inhibitor-Reference-Cited by-同舟云学术

Investigation of human flap structure-specific endonuclease 1 (FEN1) activity on primer-template models and exploration of a substrate-based FEN1 inhibitor

Published:2016-05 Issue:9 Volume:24 Page:1988-1992
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ba Sai,Zhang Hao,Lee Jasmine Yiqin,Wu Haixia,Ye Ruijuan,Huang Dejian,Li Tianhu

Funder

MOE

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference14 articles.

1. Functional regulation of FEN1 nuclease and its link to cancer

2. Flap endonuclease 1 is overexpressed in prostate cancer and is associated with a high Gleason score

3. Flap endonuclease 1 is a promising candidate biomarker in gastric cancer and is involved in cell proliferation and apoptosis

4. Complementary non-radioactive assays for investigation of human flap endonuclease 1 activity

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