Controllable Crrna Self-Transcription Aided Dual-Amplified Crispr- Cas12a Strategy for Highly Sensitive Biosensing of Fen1 Activity

Author:

Song Yang,Gao Ke,Cai Xiaoying,Cheng Wei,Ding Shijia,zhang decai,Deng Shixiong

Publisher

Elsevier BV

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference35 articles.

1. Flap endonuclease 1;L Balakrishnan;Annu. Rev. Biochem,2013

2. FEN nucleases: Bind, bend, fray, cut;R S Williams;Cell,2011

3. Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations;S E Tsutakawa;Proc. Natl. Acad. Sci. U.S.A,2020

4. Investigation of human flap structure-specific endonuclease 1 (FEN1) activity on primer-template models and exploration of a substrate-based FEN1 inhibitor;S Ba;Bioorgan. Med. Chem,2016

5. Inhibition of FEN1 increases arsenic Trioxide-Induced ROS accumulation and cell death: Novel therapeutic potential for triple negative breast cancer;X Xin;Front. Oncol,2020

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