Discovery of novel dual functional agent as PPARγ agonist and 11β-HSD1 inhibitor for the treatment of diabetes-Reference-Cited by-同舟云学术

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Discovery of novel dual functional agent as PPARγ agonist and 11β-HSD1 inhibitor for the treatment of diabetes

Published:2009-08 Issue:15 Volume:17 Page:5722-5732
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ye Yang-liang,Zhou Zhou,Zou Han-jun,Shen Yu,Xu Ti-fei,Tang Jing,Yin Hua-zhong,Chen Min-li,Leng Ying,Shen Jian-hua

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference52 articles.

1. Diabetes: New challenges for the control of disease globalisation

2. Mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes

3. Peroxisome Proliferator–Activated Receptor γ and Metabolic Disease

4. Selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice

5. The Mechanisms of Action of PPARs

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1. Development of novel thiazolidine-2,4-dione derivatives as PPAR-γ agonists through design, synthesis, computational docking, MD simulation, and comprehensive in vitro and in vivo evaluation;RSC Medicinal Chemistry;2023

2. Phenyl glycine incorporated glitazones as promising novel antidiabetic agents through PPARγ agonism: Design, synthesis and preclinical studies;European Journal of Medicinal Chemistry Reports;2022-12

3. Structural Elucidation and Bioinspired Total Syntheses of Ascorbylated Diterpenoid Hongkonoids A–D;Journal of the American Chemical Society;2018-02-07

4. Peroxisome Proliferated Activated Receptors (PPARs): Opportunities and Challenges for Ocular Therapy;Critical Reviews™ in Therapeutic Drug Carrier Systems;2018

5. Multiple Peroxisome Proliferator-Activated Receptor-Based Ligands;Methods and Principles in Medicinal Chemistry;2017-12-08

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