Small molecules targeting HIF-1α pathway for cancer therapy in recent years

Author:

Tang Wendi,Zhao Guisen

Funder

Key Research and Development Project of Shandong Province

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference101 articles.

1. Understanding the Warburg effect: the metabolic requirements of cell proliferation;Vander Heiden;Science,2009

2. Tumor microenvironment and the response to anticancer therapy;Brown;Cancer Biol Ther,2002

3. Activation of PI3 kinase/Akt/HIF-1 alpha pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma;Jiao;Int J Oncol,2012

4. Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours;Toffoli;Febs J,2008

5. The effects of endurance exercise in hypoxia on acid-base balance, potassium kinetics, and exogenous glucose oxidation;Sumi;Front Physiol,2019

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