Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors-Reference-Cited by-同舟云学术

Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors

Published:2009-10 Issue:19 Volume:17 Page:6926-6936
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Nagashima Shinya,Hondo Takeshi,Nagata Hiroshi,Ogiyama Takashi,Maeda Jun,Hoshii Hiroaki,Kontani Toru,Kuromitsu Sadao,Ohga Keiko,Orita Masaya,Ohno Kazuki,Moritomo Ayako,Shiozuka Koichi,Furutani Masako,Takeuchi Makoto,Ohta Mitsuaki,Tsukamoto Shin-ichi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. Signal transducer and activator of transcription signals in allergic disease

2. Methylation of STAT6 Modulates STAT6 Phosphorylation, Nuclear Translocation, and DNA-Binding Activity

3. Interleukin 4 Regulates Phosphorylation of Serine 756 in the Transactivation Domain of Stat6

4. Essential role of Stat6 in IL-4 signalling

5. Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

Cited by 43 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. STATs, promising targets for the treatment of autoimmune and inflammatory diseases;European Journal of Medicinal Chemistry;2024-11

2. Design, Synthesis, in Vitro, and in Silico Evaluations of 1,3,4‐Oxadiazole Derivatives Linked to the Pyrrolo[2,3‐d]pyrimidine Moieties as Potent Antimicrobial Targets;ChemistrySelect;2024-06-18

3. Synthesis and Characterization of Novel Substituted Bezaldehyde Derivatives of 4- Aminopyrrolo [2, 3-D] Pyrimidine;2023-04-06

4. DFT Analysis and Synthesis of Medicinally Important Pyrrolo[2,3-d]Pyrimidines by Using Thiamine Hydrochloride as a Recyclable Organocatalyst in Aqueous Media;Polycyclic Aromatic Compounds;2022-11-06

5. Targeting Mast Cells in Allergic Disease: Current Therapies and Drug Repurposing;Cells;2022-09-27