Design, synthesis, molecular modelling and in vitro cytotoxicity analysis of novel carbamate derivatives as inhibitors of Monoacylglycerol lipase-Reference-Cited by-同舟云学术

Design, synthesis, molecular modelling and in vitro cytotoxicity analysis of novel carbamate derivatives as inhibitors of Monoacylglycerol lipase

Published:2018-05 Issue:9 Volume:26 Page:2561-2572
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Lauria Simone,Perrotta Cristiana,Casati Silvana^ORCID,Di Renzo Ilaria,Ottria Roberta,Eberini Ivano,Palazzolo Luca,Parravicini Chiara,Ciuffreda Pierangela

Funder

Università di Milano

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference41 articles.

1. Fat signals - lipases and lipolysis in lipid metabolism and signaling;Zechner;Cell Metab,2012

2. CDNA cloning, tissue distribution, and identification of the catalytic triad of monoglyceride lipase: evolutionary relationship to esterases, lysophospholipases, and haloperoxidases;Karlsson;J Biol Chem,1997

3. Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system;Schlosburg;Nat Neurosci,2010

4. Monoacylglycerol lipase activity is a critical modulator of the tone and integrity of the endocannabinoid system;Chanda;Mol Pharmacol,2010

5. The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2-arachidonoylglycerol signalling through cannabinoid receptors;Savinainen;Acta Physiol,2012

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