Identification of a novel class of selective Tpl2 kinase inhibitors: 4-Alkylamino-[1,7]naphthyridine-3-carbonitriles-Reference-Cited by-同舟云学术

Identification of a novel class of selective Tpl2 kinase inhibitors: 4-Alkylamino-[1,7]naphthyridine-3-carbonitriles

Published:2007-10 Issue:19 Volume:15 Page:6425-6442
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Kaila Neelu,Green Neal,Li Huan-Qiu,Hu Yonghan,Janz Kristin,Gavrin Lori Krim,Thomason Jennifer,Tam Steve,Powell Dennis,Cuozzo John,Hall J. Perry,Telliez Jean-Baptiste,Hsu Sang,Nickerson-Nutter Cheryl,Wang Qin,Lin Lih-Ling

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference35 articles.

1. The Proto-Oncogene Cot Kinase Participates in CD3/CD28 Induction of NF-κB Acting through the NF-κB-Inducing Kinase and IκB Kinases

2. Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c- jun Promoter and to Cellular Transformation

3. Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.

4. Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours

5. Structure and transforming potential of the human cot oncogene encoding a putative protein kinase.

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