Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor-Reference-Cited by-同舟云学术

Design, synthesis and anti-inflammatory activity of imidazol-5-yl pyridine derivatives as p38α/MAPK14 inhibitor

Published:2021-02 Issue: Volume:31 Page:115969
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ali Eslam M.H.,Abdel-Maksoud Mohammed S.,Hassan Rasha Mohamed,Mersal Karim I.,Ammar Usama M.,Se-In Choi,He-Soo Han,Kim Hee-Kwon,Lee Anna,Lee Kyung-Tae,Oh Chang-Hyun

Funder

Korea Institute of Science and Technology

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference51 articles.

1. A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket;Tong;Nat Struct Biol,1997

2. Molecular basis of MAP kinase regulation;Peti;Protein Sci,2013

3. How antirheumatic drugs protect joints from damage in rheumatoid arthritis;Schett;Arthritis Rheumatism: Off J Am College Rheumatol,2008

4. MKP-1 reduces Aβ generation and alleviates cognitive impairments in Alzheimer’s disease models;Du;Signal Transduct Target Ther,2019

5. Design, synthesis, and biological evaluation of novel Tri-and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: Focus on optimized interactions with the enzyme’s surface-exposed front region;Laufer;J Med Chem,2008

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Facile synthesis, SC-XRD, spectroscopic characterization & key electronic properties of nicotinaldehyde based scaffolds;Journal of Molecular Structure;2025-02

2. Advances in synthesis, medicinal properties and biomedical applications of pyridine derivatives: A comprehensive review;European Journal of Medicinal Chemistry Reports;2024-12

3. Novel benzenesulfonamides as dual VEGFR2/FGFR1 inhibitors targeting breast cancer: Design, synthesis, anticancer activity and in silico studies;Bioorganic Chemistry;2024-11

4. Design and Synthesis of Novel Heterocycles Utilizing 4,6-Dimethyl-1- ((4-methylthiazol-2-yl)amino)-2-oxo-1,2-dihydropyridine-3-carbonitrile;Letters in Organic Chemistry;2024-11

5. Recent pharmacological insights about imidazole hybrids: a comprehensive review;Medicinal Chemistry Research;2024-05-13