Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy-Reference-Cited by-同舟云学术

Discovery of potent and selective spiroindolinone MDM2 inhibitor, RO8994, for cancer therapy

Published:2014-08 Issue:15 Volume:22 Page:4001-4009
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Zhang Zhuming,Ding Qingjie,Liu Jin-Jun,Zhang Jing,Jiang Nan,Chu Xin-Jie,Bartkovitz David,Luk Kin-Chun,Janson Cheryl,Tovar Christian,Filipovic Zoran M.,Higgins Brian,Glenn Kelli,Packman Kathryn,Vassilev Lyubomir T.,Graves Bradford

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference46 articles.

1. The p53 pathway: positive and negative feedback loops

2. The p53–Mdm2 module and the ubiquitin system

3. p53, the Cellular Gatekeeper for Growth and Division

4. Surfing the p53 network

5. The p53-mdm-2 autoregulatory feedback loop.

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