Design and synthesis of peptide-MCA substrates for a novel assay of histone methyltransferases and their inhibitors-Reference-Cited by-同舟云学术

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Design and synthesis of peptide-MCA substrates for a novel assay of histone methyltransferases and their inhibitors

Published:2014-02 Issue:4 Volume:22 Page:1268-1275
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Chi Hongfang,Takemoto Yasushi,Nsiama Tienabe K.,Kato Tamaki,Nishino Norikazu,Ito Akihiro,Yoshida Minoru

Funder

Chemical Genomics Research Project

RIKEN Center for Sustainable Resource Science

CREST Research Project

Japan Science and Technology Corporation

Ministry of Education, Culture, Sports, Science and Technology of Japan

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference37 articles.

1. Chromatin Structure: A Repeating Unit of Histones and DNA

2. Crystal structure of the nucleosome core particle at 2.8 Å resolution

3. The many faces of histone lysine methylation

4. Chromatin Modifications as Targets for New Anticancer Drugs

5. The complex language of chromatin regulation during transcription

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1. In-Cell Testing of Zinc-Dependent Histone Deacetylase Inhibitors in the Presence of Class-Selective Fluorogenic Substrates: Potential and Limitations of the Method;Biomedicines;2024-05-29

2. Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents;Journal of Medicinal Chemistry;2023-03-08

3. Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells;Cell Chemical Biology;2022-07

4. Non-histone methylation of SET7/9 and its biological functions;Recent Patents on Anti-Cancer Drug Discovery;2021-12-02

5. A Molecular Probe with Both Chromogenic and Fluorescent Units for Detecting Serine Proteases;Molecules;2021-01-18

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