Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors-Reference-Cited by-同舟云学术

Prodrug-based design, synthesis, and biological evaluation of N-benzenesulfonylpiperidine derivatives as novel, orally active factor Xa inhibitors

Published:2007-06 Issue:12 Volume:15 Page:4175-4192
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ishihara Tsukasa,Seki Norio,Hirayama Fukushi,Orita Masaya,Koshio Hiroyuki,Taniuchi Yuta,Sakai-Moritani Yumiko,Iwatsuki Yoshiyuki,Kaku Seiji,Kawasaki Tomihisa,Matsumoto Yuzo,Tsukamoto Shin-ichi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference47 articles.

1. Thrombin-specific inhibition by and slow cleavage of hirulog-1

2. Oral Anticoagulant Drugs

3. Efficacy and Safety of Oral Anticoagulation in Patients with Cancer

4. The coagulation cascade: initiation, maintenance, and regulation

5. Synthetic Inhibitors of Thrombin and Factor Xa

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Progress of thrombus formation and research on the structure-activity relationship for antithrombotic drugs;European Journal of Medicinal Chemistry;2022-01

2. A Novel Fragment Recommendation Workflow using Direct and Indirect Transfer of SAR According to Integrated Similarities of Scaffold Motifs and SAR Trends: Application to Identifying Factor Xa Inhibitors;Chem-Bio Informatics Journal;2017

3. Advances in Inhibitors of FXa;Current Drug Targets;2015-10-13

4. New series of 6-substituted coumarin derivatives as effective factor Xa inhibitors: Synthesis, in vivo antithrombotic evaluation and molecular docking;Bioorganic Chemistry;2014-02

5. Lewis Acid-Catalyzed Ring-Opening Functionalizations of 1,4-Epoxy-1,4-dihydronaphthalenes;Advanced Synthesis & Catalysis;2013-02-01