Design, synthesis and structure–activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists-Reference-Cited by-同舟云学术

Design, synthesis and structure–activity relationship of 4-(1,1,1,3,3,3-hexafluoro-2-hydroxyisoprop-2-yl)phenylsilane derivatives as liver X receptor agonists

Published:2022-07 Issue: Volume:66 Page:116792
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Namba Nao,Noguchi-Yachide Tomomi,Matsumoto Yuichiro,Hashimoto Yuichi,Fujii Shinya

Funder

Japan Society for the Promotion of Science

Takeda Science Foundation

Japan Agency for Medical Research and Development

Research Center for Biomedical Engineering

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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4. Activation of The Nuclear Receptor LXR by Oxysterols Defines a New Hormone Response Pathway;Lehmann;J Biol Chem,1997

5. Liver X receptors in lipid metabolism: opportunities for drug discovery;Hong;Nat Rev Drug Discovery,2014

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