Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway-Reference-Cited by-同舟云学术

Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway

Published:2022-02 Issue: Volume:55 Page:116594
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Qin Jing,Sun Xia,Ma Yingang,Cheng Yahong,Ma Qiushuang,Jing Weiqiang,Qu Sifeng,Liu Lei^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

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3. Chemoresistance evolution in triple-negative breast cancer delineated by single-cell sequencing;Kim;Cell,2018

4. Small-molecule drug discovery in triple negative breast cancer: current situation and future directions;Liao;J Med Chem,2021

5. Targeting the PI3K/AKT/mTOR pathway for the treatment of mesenchymal triple-negative breast cancer: evidence from a phase 1 trial of mTOR inhibition in combination with liposomal doxorubicin and bevacizumab;Basho;JAMA Oncol,2017

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