Synthesis and SAR of 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines as potent serotonin 5-HT6 receptor antagonists-Reference-Cited by-同舟云学术

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Synthesis and SAR of 3-arylsulfonyl-pyrazolo[1,5-a]pyrimidines as potent serotonin 5-HT6 receptor antagonists

Published:2011-02 Issue:4 Volume:19 Page:1482-1491
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ivachtchenko Alexandre V.,Golovina Elena S.,Kadieva Madina G.,Kysil Volodymyr M.,Mitkin Oleg D.,Tkachenko Sergey E.,Okun Ilya

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference19 articles.

1. 5-ht6 Receptors as Emerging Targets for Drug Discovery

2. Serotonin receptors represent highly favorable molecular targets for cognitive enhancement in schizophrenia and other disorders

3. 2-Substituted Tryptamines: Agents with Selectivity for 5-HT6 Serotonin Receptors

4. Medicinal chemistry strategies to 5-HT6 receptor ligands as potential cognitive enhancers and antiobesity agents

5. Selective 5-HT6 receptor ligands: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders

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1. Regioselective C3-halogenations of N-(pyrazolo[1,5-a]pyrimidin-7-yl)acetamides;Tetrahedron;2024-01

2. Highly selective C3-sulfenylation and C3-selenylation of 3-iodo-5-arylpyrazolo[1,5-a]pyrimidin-7-amine in water;Journal of Molecular Structure;2023-11

3. Pyrazolo - Pyrimidines as Targeted Anticancer Scaffolds - A Comprehensive Review;Medicinal Chemistry;2023-10-25

4. Synthesis of some pyrazolo[1,5-a]pyrimidine derivatives bearing carbonitrile, amidoxime, carboxamide and oxadiazole substituents using commercially available reagents;Egyptian Journal of Chemistry;2023-09-12

5. Visible-Light-Induced Regioselective C–H Sulfenylation of Pyrazolo[1,5-a]pyrimidines via Cross-Dehydrogenative Coupling;The Journal of Organic Chemistry;2023-03-14

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