Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP-Reference-Cited by-同舟云学术

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP

Published:2017-06 Issue:12 Volume:25 Page:2971-2980
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Elhalem Eleonora,Donadío Lucía Gandolfi,Zhou Xiaoling,Lewin Nancy E.,Garcia Lia C.,Lai Christopher C.,Kelley James A.,Peach Megan L.,Blumberg Peter M.,Comin María J.

Funder

The National Institute of Industrial Technology

Consejo Nacional de Investigación Científica y Tecnológica

National Institutes of Health

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference34 articles.

1. Novel “Nonkinase” Phorbol Ester Receptors: The C1 Domain Connection

2. Protein Kinase C: Structural and Spatial Regulation by Phosphorylation, Cofactors, and Macromolecular Interactions

3. PKD at the crossroads of DAG and PKC signaling

4. β2-Chimaerin in Cancer Signaling: Connecting Cell Adhesion and MAP Kinase Activation

5. Phorbol esters and neurotransmitter release: more than just protein kinase C?

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