Design, Synthesis, and Characterization of Novel sn-1 Heterocyclic DAG-Lactones as PKC Activators-Reference-Cited by-同舟云学术

Design, Synthesis, and Characterization of Novel sn-1 Heterocyclic DAG-Lactones as PKC Activators

Published:2021-07-19 Issue:15 Volume:64 Page:11418-11431
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Elhalem Eleonora¹²,Bellomo Ana¹²,Cooke Mariana³⁴,Scravaglieri Antonella¹,Pearce Larry V.⁵,Peach Megan L.⁶,Gandolfi Donadío Lucía¹²,Kazanietz Marcelo G.³,Comin María J.¹²^ORCID

Affiliation:

1. Departamento de Ingredientes Activos y Biorrefinerías, Instituto Nacional de Tecnología Industrial, Av. General Paz 5445, San Martín, Buenos Aires B1650WAB, Argentina

2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Av. General Paz 5445, San Martín, Buenos Aires B1650WAB, Argentina

3. Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

4. Department of Medicine, Einstein Medical Center Philadelphia, Philadelphia, Pennsylvania 19141, United States

5. Laboratory of Cancer Biology and Genetics, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-4255, United States

6. Basic Science Program, Chemical Biology Laboratory, Frederick National Laboratory for Cancer Research, National Institutes of Health, Frederick, Maryland 21702, United States

Funder

National Cancer Institute

Consejo Nacional de Investigaciones CientÃficas y TÃ©cnicas

Fondo para la InvestigaciÃ³n CientÃfica y TecnolÃ³gica

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00739

Reference51 articles.