Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPARγ and SUR agonists

Author:

Ibrahim Mohammed K.,Eissa Ibrahim H.,Abdallah Abdallah E.,Metwaly Ahmed M.,Radwan M.M.,ElSohly M.A.

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference54 articles.

1. Design and synthesis of 6-methyl-2-oxo-1, 2, 3, 4-tetrahydro-pyrimidine-5-carboxylic acid derivatives as PPARγ activators;Kumar;Bioorg Med Chem Lett,2007

2. PPAR agonists: multimodal drugs for the treatment of type-2 diabetes;Gross;Best Pract Res Clin Endocrinol Metab,2007

3. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor γ;Lehmann;J Biol Chem,1995

4. Sulfonylurea receptors and mechanism of sulfonylurea action;Panten;Exp Clin Endocrinol Diabetes,1996

5. Identification of a new member of the steroid hormone receptor superfamily that is activated by a peroxisome proliferator and fatty acids;Schmidt;Mol Endocrinol,1992

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