Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)-Reference-Cited by-同舟云学术

Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)

Published:2013-06 Issue:11 Volume:21 Page:2856-2867
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Lin Wen-Hsing,Hsu John T.-A.,Hsieh Shu-Yi,Chen Chiung-Tong,Song Jen-Shin,Yen Shih-Chieh,Hsu Tsu,Lu Cheng-Tai,Chen Chun-Hwa,Chou Ling-Hui,Yang Yung-Ning,Chiu Ching-Hui,Chen Ching-Ping,Tseng Ya-Ju,Yen Kuei-Jung,Yeh Ching-Fang,Chao Yu-Sheng,Yeh Teng-Kuang,Jiaang Weir-Torn

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference28 articles.

1. The role of FLT3 in haematopoietic malignancies

2. The roles of FLT3 in hematopoiesis and leukemia

3. 3-Amino-benzo[d]isoxazoles as Novel Multitargeted Inhibitors of Receptor Tyrosine Kinases

4. The discovery of receptor tyrosine kinases: targets for cancer therapy

5. Kinomics: characterizing the therapeutically validated kinase space

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