Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores-Reference-Cited by-同舟云学术

Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores

Published:2009-06 Issue:11 Volume:17 Page:3934-3958
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Kotian Pravin L.,Krishnan Raman,Rowland Scott,El-Kattan Yahya,Saini Surendra K.,Upshaw Ramanda,Bantia Shanta,Arnold Shane,Sudhakar Babu Y.,Chand Pooran

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference56 articles.

1. The coagulation cascade: initiation, maintenance, and regulation

2. Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

3. Tissue Factor Expression on Macrophages in Coronary Plaques in Patients with Unstable Angina

4. Inhibition of the Tissue Factor-Thrombin Pathway Limits Infarct Size after Myocardial Ischemia-Reperfusion Injury by Reducing Inflammation

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