Discovery and biological profile of 4-(1-aryltriazol-4-yl)-tetrahydropyridines as an orally active new class of metabotropic glutamate receptor 1 antagonist-Reference-Cited by-同舟云学术

Discovery and biological profile of 4-(1-aryltriazol-4-yl)-tetrahydropyridines as an orally active new class of metabotropic glutamate receptor 1 antagonist

Published:2008-11 Issue:22 Volume:16 Page:9817-9829
ISSN:0968-0896
Container-title:Bioorganic & Medicinal Chemistry
language:en
Short-container-title:Bioorganic & Medicinal Chemistry

Author:

Ito Satoru,Satoh Atsushi,Nagatomi Yasushi,Hirata Yukari,Suzuki Gentaroh,Kimura Toshifumi,Satow Akio,Maehara Shunsuke,Hikichi Hirohiko,Hata Mikiko,Kawamoto Hiroshi,Ohta Hisashi

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference33 articles.

1. Metabotropic glutamate receptors as novel targets for anxiety and stress disorders

2. Positive and negative allosteric modulation of metabotropic glutamate receptors: emerging therapeutic potential

3. Glutamate and Schizophrenia: Pathophysiology and Therapeutics

4. Glutamate-based therapeutic approaches: allosteric modulators of metabotropic glutamate receptors

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