Anti-atherogenic effects of the acyl-CoA:cholesterol acyltransferase inhibitor, avasimibe (CI-1011), in cultured primary human macrophages

Author:

Rodriguez Annabelle,Usher David C

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference24 articles.

1. The cholesteryl ester cycle in macrophage foam cells;Brown;J. Biol. Chem.,1980

2. Novel effects of the acyl-Coenzyme A:cholesterol acyltransferase inhibitor 58-035 on foam cell development in primary human monocyte-derived macrophages;Rodriguez;Arterioscler. Thromb. Vasc. Biol.,1999

3. Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals;Meiner;Proc. Natl. Acad. Sci. USA,1996

4. Inhibitors of acyl-CoA:cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents;Lee;J. Med. Chem.,1996

5. Stimulation of cholesterol release from rabbit foam cells by the action of a new inhibitor for acyl CoA:cholesterol acyltransferase (ACAT), HL-004;Ishii;J. Pharm. Exp. Ther.,1998

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