Improved method for the simultaneous determination of proguanil and its metabolites by high-performance liquid chromatography and solid-phase extraction of 100-μl capillary blood samples dried on sampling paper-Reference-Cited by-同舟云学术

Improved method for the simultaneous determination of proguanil and its metabolites by high-performance liquid chromatography and solid-phase extraction of 100-μl capillary blood samples dried on sampling paper

Published:1998-11 Issue:1-2 Volume:719 Page:141-149
ISSN:0378-4347
Container-title:Journal of Chromatography B: Biomedical Sciences and Applications
language:en
Short-container-title:Journal of Chromatography B: Biomedical Sciences and Applications

Author:

Bergqvist Y,Funding L,Kaneko A,Krysén B,Leek T

Publisher

Elsevier BV

Subject

General Chemistry

Reference16 articles.

1. A Metabolite of ‘Paludrine’ with High Antimalarial Activity

2. The activity of proguanil and its metabolites, cycloguanil andp-chlorophenylbiguanide, againstPlasmodium falciparum in vitro

3. Inter-subject variability in the metabolism of proguanil to the active metabolite cycloguanil in man.

4. The pharmacokinetics and activation of proguanil in man: consequences of variability in drug metabolism.

5. Geographical/Interracial Differences in Polymorphic Drug Oxidation

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2. New liquid chromatographic method for simultaneous quantification of Atovaquone and Proguanil with its active metabolite Cycloguanil in human plasma;Indian Journal of Pharmaceutical Education and Research;2014-12-16

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5. ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS DETERMINATION OF ATOVAQUONE AND PROGUANIL IN RABBIT PLASMA AND ITS APPLICATION TO A PHARMACOKINETIC STUDY;Journal of Liquid Chromatography & Related Technologies;2014-04-03