An unstructured model of metabolic and temperature dependent cell cycle arrest in hybridoma batch and fed-batch cultures-Reference-Cited by-同舟云学术

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An unstructured model of metabolic and temperature dependent cell cycle arrest in hybridoma batch and fed-batch cultures

Published:2015-01 Issue: Volume:93 Page:260-273
ISSN:1369-703X
Container-title:Biochemical Engineering Journal
language:en
Short-container-title:Biochemical Engineering Journal

Author:

García Münzer D.G.,Ivarsson M.,Usaku C.,Habicher T.,Soos M.,Morbidelli M.,Pistikopoulos E.N.,Mantalaris A.

Funder

MULTIMOD Training Network

European Commission

Publisher

Elsevier BV

Subject

Biomedical Engineering,Environmental Engineering,Bioengineering,Biotechnology

Reference70 articles.

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2. 25 years of recombinant proteins from reactor-grown cells – where do we go from here?;Hacker;Biotechnol. Adv.,2009

3. Bridging the gap: facilities and technologies for development of early stage therapeutic mAb candidates;Munro;mAbs,2011

4. Production of recombinant protein therapeutics in cultivated mammalian cells;Wurm;Nat. Biotechnol.,2004

5. Process parameter shifting: Part I. Effect of DOT, pH, and temperature on the performance of Epo-Fc expressing CHO cells cultivated in controlled batch bioreactors;Trummer;Biotechnol. Bioeng.,2006

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1. Kinetic modeling: A tool for temperature shift and feeding optimization in cell culture process development;Protein Expression and Purification;2022-10

2. Population balance modelling captures host cell protein dynamics in CHO cell cultures;PLOS ONE;2022-03-23

3. Predictive macroscopic modeling of cell growth, metabolism and monoclonal antibody production: Case study of a CHO fed-batch production;Metabolic Engineering;2021-07

4. Process‐induced cell cycle oscillations in CHO cultures: Online monitoring and model‐based investigation;Biotechnology and Bioengineering;2019-08-08

5. Multivariate analysis of metabolic parameters and optimization of antibody production using high cell density hybridoma in hollow fiber bioreactors;Biotechnology Letters;2019-07-19

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