A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines

Author:

Niepel Mario,Hafner Marc,Mills Caitlin E.,Subramanian Kartik,Williams Elizabeth H.,Chung Mirra,Gaudio Benjamin,Barrette Anne Marie,Stern Alan D.,Hu Bin,Korkola James E.,Gray Joe W.,Birtwistle Marc R.,Heiser Laura M.,Sorger Peter K.,Shamu Caroline E.,Jayaraman Gomathi,Azeloglu Evren U.,Iyengar Ravi,Sobie Eric A.,Mills Gordon B.,Liby Tiera,Jaffe Jacob D.,Alimova Maria,Davison Desiree,Lu Xiaodong,Golub Todd R.,Subramanian Aravind,Shelley Brandon,Svendsen Clive N.,Ma’ayan Avi,Medvedovic Mario,Feiler Heidi S.,Smith Rebecca,Devlin Kaylyn

Funder

Thermo Fisher

Micron,

PDX Pharmaceuticals

Susan G. Komen Foundation

Prospect Creek Foundation

NCI

NIH

AztraZeneca

Karus Therapeutics

Nanostring

Pfizer

Tesaro

Adelson Medical Research Foundation

Breast Cancer Research Foundation

Komen Research Foundation

Ovarian Cancer Research Foundation

Publisher

Elsevier BV

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Reference61 articles.

1. Reproducibility will only come with data liberation;AlQuraishi;Sci. Transl. Med.,2016

2. Trial watch: Phase II failures: 2008–2010;Arrowsmith;Nat. Rev. Drug Discov.,2011

3. Towards precision medicine;Ashley;Nat. Rev. Genet.,2016

4. Biotech giant publishes failures to confirm high-profile science;Baker;Nature,2016

5. Review of current methods, applications, and data management for the bioinformatics analysis of whole exome sequencing;Bao;Cancer Inform.,2014

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