Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines-Reference-Cited by-同舟云学术

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Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines

Published:2017-12 Issue:6 Volume:5 Page:604-619.e7
ISSN:2405-4712
Container-title:Cell Systems
language:en
Short-container-title:Cell Systems

Author:

Blattmann Peter,Henriques David,Zimmermann Michael,Frommelt Fabian,Sauer Uwe,Saez-Rodriguez Julio,Aebersold Ruedi

Funder

SystemsX.ch

Swiss National Science Foundation

European Research Council

ETH Zurich

Publisher

Elsevier BV

Subject

Cell Biology,Histology,Pathology and Forensic Medicine

Reference69 articles.

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2. Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programs;Ahlin;Drug Metab. Dispos.,2009

3. Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes;Amemiya-Kudo;J. Lipid Res.,2002

4. Systems biology and pharmacology;Berg;Clin. Pharmacol. Ther.,2010

5. A mathematical model of the sterol regulatory element binding protein 2 cholesterol biosynthesis pathway;Bhattacharya;J. Theor. Biol.,2014

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