Distribution of nitroreductive activity toward nilutamide in rat

Author:

Ask Kjetil,Décologne Nathalie,Asare Nana,Holme Jørn A.,Artur Yves,Pelczar Hélène,Camus Philippe

Publisher

Elsevier BV

Subject

Pharmacology,Toxicology

Reference64 articles.

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3. Clinical study of RU 23908 (nilutamide) in prostatic cancer;Akaza;Hinyokika Kiyo,1991

4. The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)—I. Purification and properties of a nitroreductase enzyme from Escherichia coli—A potential enzyme for antibody-directed enzyme prodrug therapy (ADEPT);Anlezark;Biochem. Pharmacol,1992

5. Human enzymes involved in the metabolic activation of the environmental contaminant 3-nitrobenzanthrone: evidence for reductive activation by human NADPH:cytochrome p450 reductase;Arlt;Cancer Res,2003

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