Empagliflozin and pirfenidone confer renoprotection through suppression of glycogen synthase kinase-3β and promotion of tubular regeneration in rats with induced metabolic syndrome

Author:

Mohamed Hoda E.,Abdelhady Merna A.,Elmaghraby Asmaa M.,Elrashidy Rania A.

Publisher

Elsevier BV

Reference47 articles.

1. Pre-treatment with empagliflozin ameliorates cisplatin induced acute kidney injury by suppressing apoptosis;Abd Elmaaboud;J. Appl. Biomed.,2019

2. Empagliflozin alleviates renal inflammation and oxidative stress in streptozotocin-induced diabetic rats partly by repressing HMGB1-TLR4 receptor axis;Ashrafi Jigheh;Iran. J. Basic Med. Sci.,2019

3. Pirfenidone is a renal protective drug: mechanisms, signalling pathways, and preclinical evidence;Bai;Eur. J. Pharmacol.,2021

4. Delayed administration of a single dose of lithium promotes recovery from AKI;Bao;J. Am. Soc. Nephrol.,2014

5. Improved mitochondrial function underlies the protective effect of pirfenidone against tubulointerstitial fibrosis in 5/6 nephrectomized rats;Chen;PLoS One,2013

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