Pirfenidone is a renal protective drug: Mechanisms, signalling pathways, and preclinical evidence

Author:

Bai Xue,Nie PingORCID,Lou YanORCID,Zhu Yuexin,Jiang Shan,Li Bing,Luo PingORCID

Publisher

Elsevier BV

Subject

Pharmacology

Reference68 articles.

1. Pirfenidone is a cardioprotective drug: mechanisms of action and preclinical evidence;Aimo;Pharmacol. Res.,2020

2. Effect of pirfenidone against vanadate-induced kidney fibrosis in rats;Al-Bayati;Biochem. Pharmacol.,2002

3. The experimental agent pirfenidone reduces pro-fibrotic gene expression in a model of tacrolimus-induced nephrotoxicity;Brook;J. Surg. Res.,2005

4. Improved mitochondrial function underlies the protective effect of pirfenidone against tubulointerstitial fibrosis in 5/6 nephrectomized rats;Chen;PLOS ONE,2013

5. Pirfenidone inhibits macrophage infiltration in 5/6 nephrectomized rats;Chen;Am. J. Physiol. Renal. Physiol.,2013

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