The SMAC mimetic LCL161 is a direct ABCB1/MDR1-ATPase activity modulator and BIRC5/Survivin expression down-regulator in cancer cells
Author:
Funder
Ministry of Science and Technology, Taiwan
National Cheng Kung University
Ministry of Education
Publisher
Elsevier BV
Subject
Pharmacology,Toxicology
Reference56 articles.
1. Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1;Alam;P. Natl. Acad. Sci. USA,2018
2. Structural insight into substrate and inhibitor discrimination by human P-glycoprotein;Alam;Science,2019
3. Design of a potent anticancer lead inspired by natural products from traditional Indian medicine;Arya;J. Biomol. Struct. Dyn.,2019
4. A computational study of the inhibition mechanisms of P-glycoprotein mediated paclitaxel efflux by kinase inhibitors;Bender;BMC Syst. Biol.,2017
5. The SMAC mimetic APG-1387 sensitizes immune-mediated cell apoptosis in hepatocellular carcinoma;Chen;Front. Pharmacol.,2018
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