SIRT5 safeguards against T-2 toxin induced liver injury by repressing iron accumulation, oxidative stress, and the activation of NLRP3 inflammasome-Reference-Cited by-同舟云学术

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SIRT5 safeguards against T-2 toxin induced liver injury by repressing iron accumulation, oxidative stress, and the activation of NLRP3 inflammasome

Published:2024-11 Issue: Volume:492 Page:117084
ISSN:0041-008X
Container-title:Toxicology and Applied Pharmacology
language:en
Short-container-title:Toxicology and Applied Pharmacology

Author:

Huang Jing,Wang Yiwen,Hu Han,He Kaifeng,Jiang Xi,Huang Rongsheng,Liu Tingting,Hu Kairao,Guo Xin,Wang Jiaxuan,Zhang Dezhi,Li Qianyong,Yang Zhengtao,Wei Zhengkai

Funder

Basic and Applied Basic Research Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Elsevier BV

Reference38 articles.

1. Oxidative stress induces mitochondrial iron overload and ferroptotic cell death;Chen;Sci. Rep.,2023

2. Activated FXR promotes xenobiotic metabolism of T-2 toxin and attenuates oxidative stress in broiler chicken liver;Dai;Chem. Biol. Interact.,2020

3. Sirt5 Is an NAD-dependent protein lysine demalonylase and desuccinylase;Du;Science (New York, N.Y.),2011

4. Structural mechanisms of NLRP3 Inflammasome assembly and activation;Fu;Annu. Rev. Immunol.,2023

5. Iron toxicity in the retina requires Alu RNA and the NLRP3 inflammasome;Gelfand;Cell Rep.,2015

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